ctsliver
LiverClock is a liver tissue-specific chronological-age clock trained by lasso on age-associated CpGs identified after adjustment for five estimated liver cell fractions; unlike HepClock, it is not hepatocyte-specific.
Model weights retain the original authors' terms; the pyaging software license does not relicense them.
| Predicts | chronological age |
| Species | Homo sapiens |
| Tissue | liver |
| Data type | DNA methylation |
| Model type | LASSO regression |
| Year | 2024 |
Use with pyaging
import pyaging as pya
pya.pred.predict_age(adata, ["ctsliver"])
Browse every clock in the pyaging Clock Catalogue.
Citation
Tong, Huige, et al. "Cell-type specific epigenetic clocks to quantify biological age at cell-type resolution." Aging 16 (2024): 14204–14237.
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