reg

Baseline chronological-age regression model from the Pasta study, using rank-transformed multi-tissue human expression.

Model weights retain the original authors' terms; the pyaging software license does not relicense them.

Predicts	chronological age
Species	Homo sapiens
Tissue	multi-tissue
Data type	transcriptomics
Model type	ridge regression
Year	2026

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["reg"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Salignon, J., et al. (2026). Pasta, a versatile transcriptomic clock, maps the chemical and genetic determinants of aging and rejuvenation. Advanced Science, e76740.

https://doi.org/10.1002/advs.76740